This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-CD44 (CD44) antibody
catalog :
ABIN118667
quantity :
0.1 mg
price :
434.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VFF-11
reactivity :
human
application :
immunohistochemistry, flow cytometry, FACS, immunohistochemistry - frozen section
citations: 2
Reference
Yu Q, Toole B, Stamenkovic I. Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function. J Exp Med. 1997;186:1985-96 pubmed
Fox S, Fawcett J, Jackson D, Collins I, Gatter K, Harris A, et al. Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms. Cancer Res. 1994;54:4539-46 pubmed
product information
Catalog Number :
ABIN118667
Product Name :
anti-CD44 (CD44) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
CD44
Product Type :
Primary
Size :
0.1 mg
List Price USD :
434.5 USD
List Of Pubmed ID :
9396767,7519124
Image Legend :
Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with CD44v4 Ab (Cat. ABIN118667) using peroxidase-conjugate and AEC chromogen. Note membrane staining of tumor cells.
Clone :
VFF-11
Isotype :
IgG1
Product Description :
CD44 variant4 is a cell surface glycoprotein expressed on lymphocytes, monocytes, and granulocytes. The CD44 Molecule belongs to a family of cellular adhesion molecule found on a wide range of normal and malignant cells in epithelial, mesothelial and haematopoietic tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been shown to be associated with metastasis and poor prognosis in certain human malignancies, such as breast cancer.Synonyms: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein I
Immunogen :
Recombinant protein corresponding to exon variant 4 of the CD44 molecule.
Reactivity :
Human
Buffer :
PBS with 0.01 % Thimerosal as preservative.
Concentration :
0.5 mg/mL
Application Summary :
Flow Cytometry (FACS),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Uniprot ID :
P16070
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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