This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (Extracellular Domain) antibody (FITC)
catalog :
ABIN118120
quantity :
0.1 mg
price :
253 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
01-03-23
reactivity :
mouse
application :
flow cytometry, FACS
citations: 3
Reference
Hasbold J, Johnson Leger C, Atkins C, Clark E, Klaus G. Properties of mouse CD40: cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies. Eur J Immunol. 1994;24:1835-42 pubmed
Hasbold J, Klaus G. B cells from CBA/N mice do not proliferate following ligation of CD40. Eur J Immunol. 1994;24:152-7 pubmed
Parry S, Holman M, Hasbold J, Klaus G. Plastic-immobilized anti-mu or anti-delta antibodies induce apoptosis in mature murine B lymphocytes. Eur J Immunol. 1994;24:974-9 pubmed
product information
Catalog Number :
ABIN118120
Product Name :
anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (Extracellular Domain) antibody (FITC)
Host Species :
Rat
Clonality :
Monoclonal
Conjugation :
FITC
Antigen :
CD40
Product Type :
Primary
Size :
0.1 mg
List Price USD :
253 USD
List Of Pubmed ID :
7519998,7512037,7517360
Image Legend :
Staining of mouse spleen cells with RAT ANTI MOUSE CD40:FITC
Clone :
01-03-23
Isotype :
IgG2a
Product Description :
CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell types, such as B cells, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts or vascular smooth muscle cells. Interaction of CD40 and its ligand CD154 (CD40L) is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. In monocytes/macrophages CD40 engagement induces production of pro-inflammatory cytokines and chemokines. CD40-CD154 interactions are also critical for development of CD4 T cell-dependent effector functions. CD40 links innate and adaptive immune responses to bacterial stimuli and serves as an important regulator affecting functions of other costimulatory molecules.Synonyms: B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5
Immunogen :
Extracellular Domain of Mouse CD40 and the Fc portion of Human IgG1. Spleen cells from immunised LOU/c rats were fused with cells of the Ag8 mouse myeloma cell line.
Epitope :
Extracellular Domain
Reactivity :
Mouse (Murine)
Buffer :
PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Concentration :
0.1 mg/mL
Application Summary :
Flow Cytometry (FACS)
Uniprot ID :
P27512
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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