This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Androgen Receptor (AR) (AA 340-356) antibody
catalog :
ABIN114765
quantity :
1 mL
price :
720.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AR441
reactivity :
human, dogs
application :
western blot, immunohistochemistry, immunohistochemistry - frozen section
citations: 3
Reference
Qiu Y, Leuschner I, Braun P. Androgen receptor expression in clinically localized prostate cancer: immunohistochemistry study and literature review. Asian J Androl. 2008;10:855-63 pubmed publisher
Rakha E, El Sayed M, Green A, Lee A, Robertson J, Ellis I. Prognostic markers in triple-negative breast cancer. Cancer. 2007;109:25-32 pubmed
Ruizeveld de Winter J. Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues. J Histochem Cytochem. 1994;42:125-6 pubmed
product information
Catalog Number :
ABIN114765
Product Name :
anti-Androgen Receptor (AR) (AA 340-356) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
Androgen Receptor
Product Type :
Primary
Size :
1 mL
List Price USD :
720.5 USD
List Of Pubmed ID :
18958349,17146782,8263324
Image Legend :
Formalin fixed paraffin embedded human prostate stained with Androgen Receptor antibody. ABIN114765
Clone :
AR441
Isotype :
IgG1
Product Description :
The androgen receptor (AR) is a 110 kDa androgen-dependent transcription factor that is a member of the steroid/nuclear receptor gene superfamily. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain. Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease and male infertility. The PI3K/Akt signaling pathway plays an important role in regulating AR activity through phosphorylation of AR at Ser213/210 and Ser791/790. Growth factors or cytokines may induce phosphorylation of AR through the PI3K/Akt pathway. Activation of the PI3K/AKt pathway is thought to have a survival role in prostate cancer by protecting cells from apoptosis.Synonyms: DHTR, Dihydrotestosterone receptor, NR3C4, Nuclear receptor subfamily 3 group C member 4
Immunogen :
BALB/C mice were injected with a synthetic peptide, amino acid 340-356 (STEDTAEYSPFKGGYTK) of Human Androgen Receptor
Epitope :
AA 340-356
Reactivity :
Dog (Canine),Human
Application Summary :
Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
P10275
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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