This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
catalog :
ABIN114222
quantity :
0.25 mg
price :
324.5 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
16A
reactivity :
mouse
application :
immunohistochemistry, immunoprecipitation, flow cytometry, FACS, immunohistochemistry - frozen section
citations: 2
Reference
Hathcock K, Hirano H, Hodes R. CD45 expression by murine B cells and T cells: alteration of CD45 isoforms in subpopulations of activated B cells. Immunol Res. 1993;12:21-36 pubmed
Bottomly K, Luqman M, Greenbaum L, Carding S, West J, Pasqualini T, et al. A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines. Eur J Immunol. 1989;19:617-23 pubmed
product information
Catalog Number :
ABIN114222
Product Name :
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
Host Species :
Rat
Clonality :
Monoclonal
Antigen :
CD45 / LCA
Product Type :
Primary
Size :
0.25 mg
List Price USD :
324.5 USD
List Of Pubmed ID :
2567241,8515182
Image Legend :
Cell source: Spleen.
Clone :
16A
Isotype :
IgG2a
Product Description :
CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.Synonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
Immunogen :
TH2 cell clones, final boost with TH2 clone D10
Reactivity :
Mouse (Murine)
Buffer :
PBS containing 0.02 % sodium azide
Concentration :
1.0 mg/mL
Application Summary :
Flow Cytometry (FACS),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Immunoprecipitation (IP)
Uniprot ID :
P06800
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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