This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Chain alpha) antibody
catalog :
ABIN111141
quantity :
0.5 mg
price :
632.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1H7
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, FACS
citations: 4
Reference
Hantel C, Lewrick F, Reincke M, Süss R, Beuschlein F. Liposomal doxorubicin-based treatment in a preclinical model of adrenocortical carcinoma. J Endocrinol. 2012;213:155-61 pubmed publisher
Beauvais D, Rapraeger A. Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation. J Cell Sci. 2010;123:3796-807 pubmed publisher
Hantel C, Lewrick F, Schneider S, Zwermann O, Perren A, Reincke M, et al. Anti insulin-like growth factor I receptor immunoliposomes: a single formulation combining two anticancer treatments with enhanced therapeutic efficiency. J Clin Endocrinol Metab. 2010;95:943-52 pubmed publisher
Li S, Kato J, Paz I, Kasuya J, Fujita Yamaguchi Y. Two new monoclonal antibodies against the alpha subunit of the human insulin-like growth factor-I receptor. Biochem Biophys Res Commun. 1993;196:92-8 pubmed
product information
Catalog Number :
ABIN111141
Product Name :
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Chain alpha) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
CD221 / IGF1R
Product Type :
Primary
Size :
0.5 mg
List Price USD :
632.5 USD
List Of Pubmed ID :
19952224,22407999,8216340,20971705
Image Legend :
Staining of human peripheral blood granulocytes with mouse anti human CD221-low endotoxin (ABIN111141)
Clone :
1H7
Isotype :
IgG1
Product Description :
CD221, a 155 kD tyrosine kinase, is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signalling proteins.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
Epitope :
Chain alpha
Reactivity :
Human
Buffer :
PBS without preservatives or stabilizers
Concentration :
1.0 mg/mL
Application Summary :
Flow Cytometry (FACS),Functional Studies (Func),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
P08069
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
antibodies-online.com facilitates researchers to find the appropriate antibodies for their respective research project. As an independent and multi-vendor marketplace for research antibodies and thanks to the cooperation with more than 120 different manufacturers, we offer a large selection of Antibodies (over 500,000), ELISA Kits (over 200,000), Secondary Antibodies (13,000), Proteins (150,000), Peptides and Isotype Controls. In addition the scientists receive news and detailed information about the individual antibodies from databases such as the PubMed and others.
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