This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Glial Fibrillary Acidic Protein (GFAP) antibody
catalog :
ABIN1107345
quantity :
0.1 mg
price :
313.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GA-8
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - frozen section
citations: 2
Reference
Rodriguez D, Gauthier F, Bertini E, Bugiani M, Brenner M, N guyen S, et al. Infantile Alexander disease: spectrum of GFAP mutations and genotype-phenotype correlation. Am J Hum Genet. 2001;69:1134-40 pubmed
Brenner M, Johnson A, Boespflug Tanguy O, Rodriguez D, Goldman J, Messing A. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet. 2001;27:117-20 pubmed
product information
Catalog Number :
ABIN1107345
Product Name :
anti-Glial Fibrillary Acidic Protein (GFAP) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
GFAP
Product Type :
Primary
Size :
0.1 mg
List Price USD :
313.5 USD
List Of Pubmed ID :
11567214,11138011
Clone :
GA-8
Isotype :
IgG1
Product Description :
GGlial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.Synonyms: Glial Fibrillary Acidic Protein
Immunogen :
GFAP from pig spinal cord.
Reactivity :
Human,Mouse (Murine),Rat (Rattus)
Buffer :
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Concentration :
0,1 mg/mL
Application Summary :
Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
P14136
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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