This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
catalog :
ABIN1105504
quantity :
0.1 mg
price :
313.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BL-2
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
citations: 2
Reference
Ngan B, Chen Levy Z, Weiss L, Warnke R, Cleary M. Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. N Engl J Med. 1988;318:1638-44 pubmed
Hockenbery D, Nunez G, Milliman C, Schreiber R, Korsmeyer S. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature. 1990;348:334-6 pubmed
product information
Catalog Number :
ABIN1105504
Product Name :
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
Bcl-2
Product Type :
Primary
Size :
0.1 mg
List Price USD :
313.5 USD
List Of Pubmed ID :
3287162,2250705
Clone :
BL-2
Isotype :
IgG1
Product Description :
Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t(14,18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
Immunogen :
Synthetic peptide corresponding to residues 41-54pf the bcl-2 protein, conjugated to thyroglobulin.
Epitope :
AA 41-54
Reactivity :
Human
Buffer :
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Concentration :
0,1 mg/mL
Application Summary :
Immunofluorescence (IF),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
P10415
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
antibodies-online.com facilitates researchers to find the appropriate antibodies for their respective research project. As an independent and multi-vendor marketplace for research antibodies and thanks to the cooperation with more than 120 different manufacturers, we offer a large selection of Antibodies (over 500,000), ELISA Kits (over 200,000), Secondary Antibodies (13,000), Proteins (150,000), Peptides and Isotype Controls. In addition the scientists receive news and detailed information about the individual antibodies from databases such as the PubMed and others.
We help scientists to find the right products in our database. Similar products can be compared, our technical hotline offers consulting and the possibility to order directly with us.