FLRT1 | American Research Products 19-C348 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

American Research Products

product type :

protein

product name :

FLRT1

catalog :

19-C348

quantity :

10 ug

price :

99.00 USD

product information

Catalog Number :

19-C348

Product Name :

FLRT1

Product Type :

Recombinant Protein

Size :

10 ug

List Price :

99.00 USD

Product Description :

FLRT1, Fibronectin Leucine Rich Transmembrane protein 1 (FLRT1) is a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins: FLRT1, FLRT2 and FLRT3, all contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The fibronectin domain of all three FLRTs can bind FGF receptors. This binding is thought to regulate FGF signaling during development. The LRR domains are responsible for both the localization of FLRTs in areas of cell contact and homotypic cell cell association. FLRT1 is expressed at brain compartmental boundaries. FLRT1 is a target for tyrosine phosphorylation mediated by FGFR1 and implicate a non-receptor Src family kinase (SFK).

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Packaging :

Recombinant Human FLRT1 was lyophilized at 1mg/ml in 20mM PBS.