This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
American Research Products
product type :
protein
product name :
Fetuin B
catalog :
19-C345
quantity :
10 ug
price :
99.00 USD
product information
Catalog Number :
19-C345
Product Name :
Fetuin B
Product Type :
Recombinant Protein
Size :
10 ug
List Price :
99.00 USD
Product Description :
Fetuin B also known as 16G2,Fetuin-like protein IRL685,Gugu,is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. It is reported that Fetuin-B is highly expressed in liver tissue, in tongue and placenta tissues. FetuinB is a paralogue of Fetuin-A. Fetuin A and B display similarities and differences in their characteristics, however,they share only 20% amino acid sequence identity. The amounts of Fetuin B in human serum, unlike Fetuin A, vary with gender and are higher in females than in males. Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than fetuin-A. Fetuin-B expression is decreased in fetuin-A deficient knock-out mice. The expression of Fetuin-B has been shown to be regulated by FXR (farnesoid X receptor), a nuclear receptor activated by bile acids. Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice. The function of Fetuin B is still not fully characterized.
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Packaging :
Recombinant Human Fetuin B was lyophilized at 1mg/ml in 20mM PBS.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
http://www.arp1.com
(800) 832-2611
headquarters: USA