This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
American Research Products
product type :
protein
product name :
CD40/TNFRSF5
catalog :
19-C319
quantity :
10 ug
price :
99.00 USD
product information
Catalog Number :
19-C319
Product Name :
CD40/TNFRSF5
Product Type :
Recombinant Protein
Size :
10 ug
List Price :
99.00 USD
Product Description :
CD40 is a type I transmembrane glycoprotein that belongs to the TNF receptor superfamily. CD40 is expressed in B cells, follicular dendritic cells,dendritic cells, activated monocytes, macrophages,endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by the cysteine rich repeat regions. Interaction of CD40 with its ligand,CD40L, leads to aggregation of CD40 molecules,which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (Adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Packaging :
Recombinant Human CD40 was lyophilized at 1mg/ml in 20mM PBS.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
http://www.arp1.com
(800) 832-2611
headquarters: USA