This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
American Research Products
product type :
protein
product name :
SUMO2
catalog :
19-C176
quantity :
10 ug
price :
99.00 USD
product information
Catalog Number :
19-C176
Product Name :
SUMO2
Product Type :
Recombinant Protein
Size :
10 ug
List Price :
99.00 USD
Product Description :
Small ubiquitin-related modifier 2, also known as Ubiquitin-like protein SMT3B, SMT3 homolog 2, SMT3A, SMT3H2, is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO2 can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Packaging :
Recombinant Human SUMO2 was lyophilized at 1mg/ml in 20mM PBS.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
http://www.arp1.com
(800) 832-2611
headquarters: USA