This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
American Research Products
product type :
protein
product name :
SUMO1
catalog :
19-C175
quantity :
10 ug
price :
99.00 USD
product information
Catalog Number :
19-C175
Product Name :
SUMO1
Product Type :
Recombinant Protein
Size :
10 ug
List Price :
99.00 USD
Product Description :
Small ubiquitin-related modifier 1, also known as Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein UBL1, GAP-modifying protein 1, Ubiquitin-like protein SMT3C, SUMO1, UBL1, PIC1, is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Packaging :
Recombinant Human SUMO1 was lyophilized at 1mg/ml in 20mM PBS.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
http://www.arp1.com
(800) 832-2611
headquarters: USA