This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
American Research Products
product type :
protein
product name :
PP2C alpha/PPM1A
catalog :
19-C161
quantity :
10 ug
price :
99.00 USD
product information
Catalog Number :
19-C161
Product Name :
PP2C alpha/PPM1A
Product Type :
Recombinant Protein
Size :
10 ug
List Price :
99.00 USD
Product Description :
Protein phosphatase 1A(PPM1A) is a member of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1A has a broad specificity. PPM1A negatively regulates the activities of MAP kinases and MAP kinase kinases. Also, it negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. In addition, PPM1A can dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control.
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Packaging :
Recombinant Human PPM1A was lyophilized at 1mg/ml in 20mM PBS.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
http://www.arp1.com
(800) 832-2611
headquarters: USA