Oncostatin M/OSM | American Research Products 19-C099 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

American Research Products

product type :

protein

product name :

Oncostatin M/OSM

catalog :

19-C099

quantity :

10 ug

price :

149.00 USD

product information

Catalog Number :

19-C099

Product Name :

Oncostatin M/OSM

Product Type :

Recombinant Protein

Size :

10 ug

List Price :

149.00 USD

Product Description :

Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator which Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological activities through specific cell surface receptors. The low affinity LIF receptor which share the similarity of containing protein gp130 has now been identified to be a component of a high- affinity OSM receptor that will transduce OSM signals. OSM has also been shown to play a role in both pro and anti-inflammatory actions. OSM may also be involved in many biometabolism processes including liver development, haematopoeisis, inflammation, bone formation and destruction and possibly CNS development.

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Packaging :

Recombinant Human Oncostatin M was lyophilized at 1mg/ml in 20mM PBS.