CXCL7/NAP-2 | American Research Products 19-C056 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

American Research Products

product type :

protein

product name :

CXCL7/NAP-2

catalog :

19-C056

quantity :

10 ug

price :

149.00 USD

product information

Catalog Number :

19-C056

Product Name :

CXCL7/NAP-2

Product Type :

Recombinant Protein

Size :

10 ug

List Price :

149.00 USD

Product Description :

Human Chemokine (C-X-C motif) ligand 7 (hCXCL7),also known as neutrophil activating peptide 2 (NAP-2),is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2,chemoattracts and activates neutrophils. CXCL7,Connective Tissue Activating Protein III (CTAPIII) and betathrombogulin( betaTG),are proteolytically processed carboxylterminal fragments of platelet basic protein (PBP) which is found in the alphagranules of human platelets. Although CTAPIII, betaTG and PBP represent amino-terminal extended variants of NAP2 and possess the same CXC chemokine domains, these proteins do not exhibit CXCL7/NAP2 activity. CXCL7 induces cell migration through the G-protein-linked receptor CXCR-2.

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Packaging :

Recombinant Human CXCL7 was lyophilized at 1mg/ml in 20mM PBS,150mM NaCl.