IL-1 beta/IL-1F2 | American Research Products 19-C042 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

American Research Products

product type :

protein

product name :

IL-1 beta/IL-1F2

catalog :

19-C042

quantity :

10 ug

price :

149.00 USD

product information

Catalog Number :

19-C042

Product Name :

IL-1 beta/IL-1F2

Product Type :

Recombinant Protein

Size :

10 ug

List Price :

149.00 USD

Product Description :

IL-1 is a name that designates two proteins, IL-1alpha and IL-1beta, that are the products of distinct genes, but recognize the same cell surface receptors. IL-1alpha and IL-1beta are structurally related polypeptides that show apprximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-1beta, designated interleukin 1beta-converting enzyme (ICE), has been described. Mature human and mouse IL-1beta share approximately 75% amino acid sequence identity and human IL-1beta has been found to be active on murine cell lines.

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Packaging :

Recombinant Mouse IL1b was lyophilized at 1mg/ml in 20mM PBS.