TRAIL/APO-2L/TNFSF10 | American Research Products 19-C022 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

American Research Products

product type :

protein

product name :

TRAIL/APO-2L/TNFSF10

catalog :

19-C022

quantity :

10 ug

price :

99.00 USD

product information

Catalog Number :

19-C022

Product Name :

TRAIL/APO-2L/TNFSF10

Product Type :

Recombinant Protein

Size :

10 ug

List Price :

99.00 USD

Product Description :

Human Apo2 ligand or tumor necrosis factor (TNF)-related apoptosis-inducing ligand (Apo2L/TRAIL/TNFSF10)is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. Apo2L /TRAIL can interact with several distinct receptors. Two of these receptors which belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. Apo2L/TRAIL is promising for cancer therapy based on the fact that it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells. Recombinant Human Apo2L/TRAIL is composed of C terminal extracellular domain including THD.

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Packaging :

Sterile and lyophilized aliquots with a 0.2um filtered protein solution containing 20mM Tris-HCl pH8.0,150mM NaCl.