This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
American Research Products
product type :
protein
product name :
IL-17/IL-17A
catalog :
19-C021
quantity :
10 ug
price :
99.00 USD
product information
Catalog Number :
19-C021
Product Name :
IL-17/IL-17A
Product Type :
Recombinant Protein
Size :
10 ug
List Price :
99.00 USD
Product Description :
IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As interleukin-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. Interleukin-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Packaging :
Lyophilized from a concentrated (1mg/ml) solution containing no additives.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
http://www.arp1.com
(800) 832-2611
headquarters: USA