This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
American Research Products
product type :
protein
product name :
CD40 Ligand/TNFSF5
catalog :
19-C011
quantity :
10 ug
price :
99.00 USD
product information
Catalog Number :
19-C011
Product Name :
CD40 Ligand/TNFSF5
Product Type :
Recombinant Protein
Size :
10 ug
List Price :
99.00 USD
Product Description :
CD40 Ligand (CD40L), also known as CD154, TNFSF5, TRAP or gp39, is a type II transmembrane glycoprotein that belongs to the TNF superfamily.Like other TNF superfamily members, CD40L exists as a trimer, in membrane bound and soluble form, both of which are bioactive. CD40L is a ligand for CD40, its ligation also initiates signal transduction in CD40L expressing cells.CD40L is differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2.
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Packaging :
CD40L is lyophilized from a sterile concentrated solution (1mg/ml) with 10mM Sodium Phosphate pH=7.5.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
http://www.arp1.com
(800) 832-2611
headquarters: USA