product summary
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company name :
American Research Products
product type :
antibody
product name :
Anti-C4d, Human
catalog :
12-5000
quantity :
250 ul
price :
339.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
immunohistochemistry, immunohistochemistry - paraffin section
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 4A
Reese S, Wilson N, Huang G, Redfield R, Zhong W, Djamali A. Calcineurin Inhibitor Minimization With Ixazomib, an Investigational Proteasome Inhibitor, for the Prevention of Antibody Mediated Rejection in a Preclinical Model. Transplantation. 2015;99:1785-95 pubmed publisher
Anzai A, Choi J, He S, Fenn A, Nairz M, Rattik S, et al. The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes. J Exp Med. 2017;214:3293-3310 pubmed publisher
Miller D, Roden A, Gamez J, Tazelaar H. Detection of C4d deposition in cardiac allografts: a comparative study of immunofluorescence and immunoperoxidase methods. Arch Pathol Lab Med. 2010;134:1679-84 pubmed publisher
Ali S, Shah V, McKinnon R, Van Harn M, Janakiraman N. Frequent expression of C4d in hepatic graft-versus-host disease: potential clue for diagnosis and distinguishing acute and chronic form. Transpl Immunol. 2010;23:77-80 pubmed publisher
Fedson S, Daniel S, Husain A. Immunohistochemistry staining of C4d to diagnose antibody-mediated rejection in cardiac transplantation. J Heart Lung Transplant. 2008;27:372-9 pubmed publisher
product information
Catalog Number :
12-5000
Product Name :
Anti-C4d, Human
Host Species :
Rabbit
Clonality :
polyclonal
Conjugation :
Purified
Product Type :
Rabbit Polyclonal
Size :
250 ul
List Price :
339.00 USD
Product Description :
Rabbit polyclonal Antibody to human C4d
Immunogen :
Synthetic peptide specific for human C4d conjugated to KLH (keyhole limpet hemocyanin)
Specificity :
Human C4d
Application Summary :
Immunohistochemistry, suitable for frozen section and paraffin embedded tissue. Pretreatment of sample is highly recommended for antigen retrieval
Storage :
2-8°C for immediate use, or at -20°C (aliquot). AVOID repeated freezing and thawing
General References :
1. Akalin, E., Dinavahi, R., Friedlander, R., Ames, S., de Boccardo, G., Sehgal, V., Schröppel, B., Bhaskaran, M., Lerner, S., Fotino, M., Murphy, B., Bromberg, J.S. Addition of Plasmapheresis Decreases the Incidence of Acute Antibody-Mediated Rejection in Sensitized Patients with Strong Donor-Specific Antibodies. (2008), Clinical Journal of the American Society of Nephrology, 3: 1160-1167. 2. Astor, T. L., Galantowicz, M., Phillips, A., Palafox, J. and Baker, P. (2009), Pulmonary Capillaritis as a Manifestation of Acute Humoral Allograft Rejection Following Infant Lung Transplantation. American Journal of Transplantation, 9: 409–412.3. Crystal P. Jenkins, Diana M. Cardona, Jennifer N. Bowers, Bahram R. Oliai, Robert W. Allan, and Sigurd J. Normann (2010) The Utility of C4d, C9, and Troponin T Immunohistochemistry in Acute Myocardial Infarction. Archives of Pathology & Laboratory Medicine: February 2010, Vol. 134, No. 2, pp. 256-263.4. Csaba Galambos, Brian Feingold, and Steven A. Webber (2008) Characterization of C4d Immunostaining Utilizing Paraffin-Embedded Tissue of Nonpresensitized Pediatric Heart Transplant Patients. Pediatric and Developmental Pathology: May 2008, Vol. 11, No. 3, pp. 181-184.5. De Kort, H., Munivenkatappa, R. B., Berger, S. P., Eikmans, M., Van Der Wal, A., De Koning, E. J., Van Kooten, C., De Heer, E., Barth, R. N., Bruijn, J. A., Philosophe, B., Drachenberg, C. B. and Bajema, I. M. (2010), Pancreas Allograft Biopsies with Positive C4d Staining and Anti-Donor Antibodies Related to Worse Outcome for Patients. American Journal of Transplantation, 10: 1660–1667.6. Fedson, S.E., Daniel, S.S., Husain, A.N. (2008), Immunohistochemistry Staining of C4d to Diagnose Antibody-mediated Rejection in Cardiac Transplantation. The Journal of Heart and Lung Transplantation, 27: 372-379.7. Hisashi, Y., Yamada, K., Kuwaki, K., Tseng, Y.-L., Dor, F. J. M. F., Houser, S. L., Robson, S. C., Schuurman, H.-J., Cooper, D. K. C., Sachs, D. H., Colvin, R. B. and Shimizu, A. (2008), Rejection of Cardiac Xenografts Transplanted from alpha1,3-Galactosyltransferase Gene-Knockout (GalT-KO) Pigs to Baboons. American Journal of Transplantation, 8: 2516–2526.8. Rafiq, M. A., De Boccardo, G., Schröppel, B., Bromberg, J. S., Sehgal, V., Dinavahi, R., Murphy, B. and Akalin, E. (2009), Differential outcomes in 3 types of acute antibody-mediated rejection. Clinical Transplantation, 23: 951–957.9. Shimizu, A., Hisashi, Y., Kuwaki, K., Tseng, YL., Dor, F.J.M.F., Houser, S.L., Robson, S.C., Schuurman, HJ., Cooper, D.K.C., Sachs, D.H., Yamada, K., Colvin, R.B. Thrombotic Microangiopathy Associated with Humoral Rejection of Cardiac Xenografts from alpha1,3-Galactosyltransferase Gene-Knockout Pigs in Baboons. (2008), American Journal of Pathology, 172(6): 1471–1481. 10. Shimizu, A., Yamada, K., Yamamoto, S., Lavelle, J.M., Barth, R.N., Robson, S.C., Sachs, D.H., Colvin, R.B. (2005), Thrombotic Microangiopathic Glomerulopathy in Human Decay Accelerating Factor–Transgenic Swine-to-Baboon Kidney Xenografts. J Am Soc Nephrol, 16: 2732-2745. 11. Torrealba, J. R., Samaniego, M., Pascual, J., Becker, Y., Pirsch, J., Sollinger, Hans., Odorico, J. (2008), C4d-Positive Interacinar Capillaries Correlates With Donor-Specific Antibody-Mediated Rejection in Pancreas Allografts. Transplantation, 86: 1849-1856.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
www.arp1.com
(800) 832-2611
headquarters: USA