protein

CCL14, 20-93aa, Human, His tag, E.coli, Recombinant

11-CCL-14HT

20 ug

169.00 USD

CCL14, 20-93aa, Human, His tag, E.coli, Recombinant

Recombinant Protein

20 ug

169.00 USD

CCL14, also known as Chemokine (C-C motif) ligand 14, is member of a superfamily of inducible, secreted, proinflammatory cytokines. It has weak activities on human monocytes and acts via receptors that also recognize MIP-1alpha. It also enhances the proliferation of CD34 myeloid progenitor cells. The processed form of CCL14, designated HCC-1(9-74), is a chemotactic factor that attracts monocytes, eosinophils and T cells and is a ligand for CCR1, CCR3 and CCR5. Recombinant human CCL14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

> 95% by SDS - PAGE

Liquid. In Phosphate Buffered Saline pH7.4 containing 10% glycerol

0.5 mg/ml (determined by Bradford assay)

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Munch J., et al. (2002) Antimicrob Agents Chemother. 46:982-990.Blain K.Y., et al. (2007) Biochemistry. 46:10008-10015.