product summary
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company name :
American Research Products
product type :
protein
product name :
BMP- 4, 293-408aa, Human, Recombinant, E.coli
catalog :
11-BMP-4H
quantity :
10 ug
price :
109.00 USD
more info or order :
American Research Products product webpage
product information
Catalog Number :
11-BMP-4H
Product Name :
BMP- 4, 293-408aa, Human, Recombinant, E.coli
Product Type :
Recombinant Protein
Size :
10 ug
List Price :
109.00 USD
Product Description :
Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Purity :
> 95% by SDS - PAGE
Packaging :
Liquid. In 10mM Sodium citrate buffer (pH 3.5), 10% glycerol
Concentration :
0.5 mg/ml (determined by Bradford assay)
Storage :
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
General References :
Moon BS., et al. (2009) Exp Mol Med. 41(2):116-25.Li BC., et al. (2009) J Trauma. 66(2):450-6
more info or order :
American Research Products product webpage
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
www.arp1.com
(800) 832-2611
headquarters: USA