product summary
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company name :
American Research Products
product type :
antibody
product name :
Anti-MLDP (OXPAT/PAT-1)
catalog :
03-GP31
quantity :
25 ul
price :
209.00 USD
clonality :
polyclonal
host :
guinea pigs
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 4
Pulinilkunnil T, Kienesberger P, Nagendran J, Sharma N, Young M, Dyck J. Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity. Int J Obes (Lond). 2014;38:205-15 pubmed publisher
Sitnick M, Basantani M, Cai L, Schoiswohl G, Yazbeck C, Distefano G, et al. Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes. 2013;62:3350-61 pubmed publisher
Hsieh K, Lee Y, Londos C, Raaka B, Dalen K, Kimmel A. Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets. J Cell Sci. 2012;125:4067-76 pubmed publisher
Harris L, Shew T, Skinner J, Wolins N. A single centrifugation method for isolating fat droplets from cells and tissues. J Lipid Res. 2012;53:1021-5 pubmed publisher
Kienesberger P, Pulinilkunnil T, Sung M, Nagendran J, Haemmerle G, Kershaw E, et al. Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction. Mol Cell Biol. 2012;32:740-50 pubmed publisher
Li M, Paran C, Wolins N, Horowitz J. High muscle lipid content in obesity is not due to enhanced activation of key triglyceride esterification enzymes or the suppression of lipolytic proteins. Am J Physiol Endocrinol Metab. 2011;300:E699-707 pubmed publisher
Newsom S, Schenk S, Li M, Everett A, Horowitz J. High fatty acid availability after exercise alters the regulation of muscle lipid metabolism. Metabolism. 2011;60:852-9 pubmed publisher
Skinner J, Shew T, Schwartz D, Tzekov A, Lepus C, Abumrad N, et al. Diacylglycerol enrichment of endoplasmic reticulum or lipid droplets recruits perilipin 3/TIP47 during lipid storage and mobilization. J Biol Chem. 2009;284:30941-8 pubmed publisher
product information
Catalog Number :
03-GP31
Product Name :
Anti-MLDP (OXPAT/PAT-1)
Host Species :
Guinea Pig
Clonality :
polyclonal
Conjugation :
Purified
Product Type :
Guinea Pig Polyclonal (GP31)
Size :
25 ul
List Price :
209.00 USD
Product Description :
Guinea pig polyclonal to MLDP (OXPAT/PAT-1). Polypeptide reacting: MLDP = myocardial lipid droplet protein (also described as OXPAT/PAT-1), MW 50,844 (calculated from aa sequence data); apparent Mr 52,000 (after SDS-PAGE).
Immunogen :
Synthetic Peptide (C-terminal, aa 451-463 of human MLDP). Sequence: CPVKHTLMPELDF
Specificity :
MLDP pertains to the PAT-family proteins, covering the surface of cytoplasmic lipid droplets and sharing a homologous domain called PAT. Additional PAT proteins include adipophilin (ADRP), perilipin, and TIP47 which are expressed in differentiation-related stages of lipid metabolism
Application Summary :
Immunohistochemistry on cells and frozen sections Immunoblotting (Western, ECL)
Storage :
2-8°C
General References :
Wolins, NE. et al. (2006) Diabetes 55: 3418-3428Wolins, NE. et al. (2006) FEBS Letter 580: 5484-5491Yamaguchi, T et al. (2006) J Biol Chem 281: 14232-14240
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
www.arp1.com
(800) 832-2611
headquarters: USA