Anti-Desmoglein 1+2 | American Research Products 03-65002 product information

product summary

company name :

American Research Products

product type :

antibody

product name :

Anti-Desmoglein 1+2

catalog :

03-65002

quantity :

1 ml

price :

109.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

American Research Products product webpage

product information

Catalog Number :

03-65002

Product Name :

Anti-Desmoglein 1+2

Host Species :

Mouse

Clonality :

monoclonal

Conjugation :

Purified

Product Type :

Mouse monoclonal

Size :

1 ml

List Price :

109.00 USD

Clone :

DG 3.10

Isotype :

IgG1

Product Description :

DG 3.10 recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells; does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium- derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting : Mr 165 000 Desmoglein, ""band 3"" polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain (""RUD"" of the cytoplasmic C-terminal part of the polypeptide

Immunogen :

Band 3"" polypeptide of isolated desmosomes from bovine muzzle epidermis

Specificity :

Reactivities on cultured cell line: A-431, MCF-7, TR-146, PLC and various other human epithelial cell lines; bovine BMGE+H, BMGE-H, MDBK

Application Summary :

Immunohistochemistry, suitable for frozen tissue, for paraffin- embedded tissue after microwave application Immunofluorescence Immunoblotting (Western)

Storage :

2-8°C for immediate use, or at -20°C (aliquot)

General References :

Koch, P.J.et al. (1990) Eur. J. Cell Biol. 53: 1-12Schmelz, M. et al. (1986) Eur. J. Cell Biol. 42: 184-199Wheeler, GN. et al. (1991) Eur. J. Cell Biol. 88: 4796-4800Schmelz, M. & Franke, WW. (1993) Eur. J. Cell Biol. 61: 274-298Schäfer, S. et al. (1994) Exp. Cell Res 211: 391-399Schäfer, S. et al. (1996) Differentiation 60: 99-108Hatzfeld, M. et al. (2000) J. Cell Biol. 149: 209-222Caldelari, R. et al. (2001) j. cell Biol. 153: 823-834

more info or order :

American Research Products product webpage