Anti-Uroplakin III | American Research Products 03-610108 product information

product summary

company name :

American Research Products

product type :

antibody

product name :

Anti-Uroplakin III

catalog :

03-610108

quantity :

200 ul

price :

129.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

American Research Products product webpage

product information

Catalog Number :

03-610108

Product Name :

Anti-Uroplakin III

Host Species :

Mouse

Clonality :

monoclonal

Conjugation :

Purified

Product Type :

Mouse monoclonal

Size :

200 ul

List Price :

129.00 USD

Clone :

AU1

Isotype :

IgG1

Product Description :

Mouse Monoclonal Antibody to Uroplakin III. Uroplakin is a membrane glycoprotein (47 kD) and has been shown to be a specific marker of terminal urothelial differentia- tion (Wu et al., 1993, 1994).

Immunogen :

Asymmetric unit membrane (AUM) preparation from bovine urinary bladder

Specificity :

Mab AU1 reacts specifically with uroplakin III present in the superficial cell layer of the urothelium. The binding region has been localized on the extracellular part of the antigen. Together with the uroplakins UP Ia, UP Ib and UP II, uroplakin III contributes in constituting the asym- metrical unit membrane of the plaques of urothelial superficial (um- brella) cells.

Application Summary :

Immunoblotting (western) Immunohistochemistry of paraffin-embedded tissue (not for frozen sections!) using a heat-induced retrieval method (e.g. microwave treatment) Not to be used for Frozen sections

Storage :

2-8°C for immediate use, or at -20°C (aliquot)

General References :

Wu, XR & Sun TT (1993) J. Cell Sci. 106: 31-43Wu, XR et al. (1994) J. Biol. Chem. 269: 13716-13724 Moll R et al. (1995). Am. J. Pathol. 147: 1383-1397Romih R et al. (1998) Histochem. Cell Biol, 109: 263-269Kauffmann, O. et al. (2000) Am. J. Clin. Pathol. 113: 683-687Hu P et al. (2000) J. Cell Biol. 151: 961-971Riedel I et al. (2001) Virchows Arch. 438: 181-191Liang, F-X. et al. (2001) Biochem J. 355: 13-18

more info or order :

American Research Products product webpage