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company name :
American Research Products
product type :
antibody
product name :
Anti-TLR7
catalog :
01-2450
quantity :
200 ul
price :
169.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
more info or order :
product information
Catalog Number :
01-2450
Product Name :
Anti-TLR7
Host Species :
Mouse
Clonality :
monoclonal
Conjugation :
Purified
Product Type :
Mouse Monoclonal
Size :
200 ul
List Price :
169.00 USD
Clone :
4F4
Product Description :
TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7,8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.
Immunogen :
Recombinant human TLR7 (451-500aa) purified from E. coli
Specificity :
TLR7
Concentration :
0.1mg/ml
Storage :
-20°C (aliquot), Avoid repeated freeze and thaw cycles.
General References :
Lee J., et al. (2003) Proc. Natl. Acad. Sci. USA. 100, 6646-6651 Crozat k., et al. (2004) Proc. Natl. Acad. Sci. USA. 101, 6835-6836 Muzio M., et al. (1998) J. Exp. Med. 187, 2097-2101 Horng T., et al. (2002) Nature 420, 329-333
more info or order :
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
Waltham, MA 02452
orders@arp1.com
www.arp1.com(800) 832-2611
headquarters: USA