Anti-Hsp27 | American Research Products 01-2439 product information

product summary

company name :

American Research Products

product type :

antibody

product name :

Anti-Hsp27

catalog :

01-2439

quantity :

200 ul

price :

169.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

more info or order :

American Research Products product webpage

product information

Catalog Number :

01-2439

Product Name :

Anti-Hsp27

Host Species :

Mouse

Clonality :

monoclonal

Conjugation :

Purified

Product Type :

Mouse Monoclonal

Size :

200 ul

List Price :

169.00 USD

Clone :

2A5

Product Description :

Hsp27 (also known as the Estrogen-Regulated 24k protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPkAP kinase 2 and the stress-activated protein kinase SAPk2 (p38). Hsp27 forms a multimeric complex within cells, and its primary chaperone function, like other small Hsps, appears to be the stabilization of denatured or aggregated proteins in a refolding competent state.

Immunogen :

Recombinant human Hsp27 (1-205aa) purified from E. coli

Specificity :

Hsp27

Concentration :

0.1mg/ml

Storage :

-20°C (aliquot), Avoid repeated freeze and thaw cycles.

General References :

Ehrnsperger M, et al., (1997) EMBO J 16:221-229 Steve J, et al., (2000) Mol Cell Biol 20(20):7602–7612 Butt E, et al., (2001) J Biol Chem 276:7108-7113 Michael, et al., (2002) Cell Stress Chsperones 7(3):281–296

more info or order :

American Research Products product webpage