product summary
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company name :
American Research Products
product type :
antibody
product name :
Anti-NKp46
catalog :
01-2426
quantity :
200 ul
price :
169.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
product information
Catalog Number :
01-2426
Product Name :
Anti-NKp46
Host Species :
Mouse
Clonality :
monoclonal
Conjugation :
Purified
Product Type :
Mouse Monoclonal
Size :
200 ul
List Price :
169.00 USD
Clone :
n1D9
Product Description :
A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel Nk cell-specific molecule involved in human Nk cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in Nk cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
Immunogen :
Recombinant human Nkp46 (22-255aa) purified from E. coli
Specificity :
NKp46
Concentration :
0.1mg/ml
Storage :
-20°C (aliquot), Avoid repeated freeze and thaw cycles.
General References :
Sivori, S. et al., (1997) J. Exp. Med. 186:1125-36. Pessino, A. et al., (1998) J. Exp. Med. 188:953-60.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
www.arp1.com
(800) 832-2611
headquarters: USA