Anti-PP2C alpha | American Research Products 01-2420 product information

product summary

company name :

American Research Products

product type :

antibody

product name :

Anti-PP2C alpha

catalog :

01-2420

quantity :

200 ul

price :

169.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

more info or order :

American Research Products product webpage

product information

Catalog Number :

01-2420

Product Name :

Anti-PP2C alpha

Host Species :

Mouse

Clonality :

monoclonal

Conjugation :

Purified

Product Type :

Mouse Monoclonal

Size :

200 ul

List Price :

169.00 USD

Clone :

p6c7

Product Description :

Protein phosphatase 2C(PP2Calpha) is a Mn ²+ - or Mg ²+ -dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNk MAPk pathways and regulates cellular stress response in eukaryotes. The PPM(metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2Calpha, the prototypical member of the PPM family.

Immunogen :

Recombinant human PP2Calpha (1-382aa) purified from E. coli

Specificity :

PP2C alpha

Concentration :

0.1mg/ml

Storage :

-20°C (aliquot), Avoid repeated freeze and thaw cycles.

General References :

Lin X, et al., (2006) Cell. 125(5): 915-928 Duan X, et al., (2006) J Biol Chem. 281(48):36526-32

more info or order :

American Research Products product webpage