protein

Stathmin, 1-149aa, Human, His-tagged, Recombinant, E.coli

01-2013

10 ug

149.00 USD

Stathmin, 1-149aa, Human, His-tagged, Recombinant, E.coli

Recombinant Protein

10 ug

149.00 USD

Stathmin is a ubiquitous phosphoprotein proposed to play a general role as an intracellular relay integrating diverse regulatory signals of the cellular environment. Also, Stathmin protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. The role of Stathmin in regulation of the cell cycle causes it to be an oncoprotein (Oncoprotein 18, op18). When Stathmin is mutated and not functioning properly, this protein can cause uncontrolled cell proliferation. Recombinant human Stathmin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

> 95% by SDS - PAGE

Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

1 mg/ml (determined by Bradford assay)

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Maucuer A., et al. (1990). FEBS Lett. 264(2):275-8Sobel A., et al. (1991). Trends Biochem Sci. 16(8):301-5Steinmetz MO., et al. (2007). J Struct Biol. 158(2):137-47