product summary
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company name :
American Research Products
product type :
protein
product name :
PSMA7, 1-248aa, Human, His-tagged, Recombinant, E.coli
catalog :
01-2011
quantity :
20 ug
price :
169.00 USD
product information
Catalog Number :
01-2011
Product Name :
PSMA7, 1-248aa, Human, His-tagged, Recombinant, E.coli
Product Type :
Recombinant Protein
Size :
20 ug
List Price :
169.00 USD
Product Description :
Proteasome alpha 7, PSMA7, is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. PSMA7, belonged to the peptidase T1A family, is a 20S core alpha subunit of proteasome. This protein was found to interact specifically with two subdomains of HIF-1alpha and inhibited the transactivation function of HIF-1alpha under both normoxic and hypoxia-mimicking conditions. Recombinant PSMA7 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Purity :
> 90% by SDS - PAGE
Packaging :
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl
Concentration :
1 mg/ml (determined by Bradford assay)
Storage :
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
General References :
Cho S., et al. (2001) FEBS Lett. 498(1):62-6.Dong J,, et al. (2004) J Biol Chem. 279(20):21334-42.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
www.arp1.com
(800) 832-2611
headquarters: USA