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company name :
American Research Products
product type :
protein
product name :
HIF1AN, 1-349aa, Human, Recombinant, E.coli
catalog :
01-2009
quantity :
20 ug
price :
169.00 USD
more info or order :
American Research Products product webpage
product information
Catalog Number :
01-2009
Product Name :
HIF1AN, 1-349aa, Human, Recombinant, E.coli
Product Type :
Recombinant Protein
Size :
20 ug
List Price :
169.00 USD
Product Description :
Description: Hypoxia-inducible factor 1, alpha subunit inhibitor (HIF1AN), a member of the Fe2+ and 2-oxoglutarate-dependent dioxygenase superfamily, is protein that hydoxylates a specific asparagine residue (Asn-803) within the HIF1alpha C-terminal transactivation domain. In normoxia, the HIF1AN-mediated hydroxylation of the HIF1alpha transactivation domain results in blockage of the HIF1alpha-p300/CBP interaction and represses transcriptional activity of HIF1alpha-targeted genes. Recombinant human HIF1AN protein was expressed in E.coli and purified by using conventional chromatography techniques.
Purity :
> 90% by SDS - PAGE
Packaging :
Liquid. In 20 mM Tris-HCl buffer (pH 8.0)
Concentration :
1 mg/ml (determined by Bradford assay)
Storage :
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
General References :
Fukuba H., et al. (2008) Neurosci Lett. 433(3):209-14.Li J., et al. (2007) Mol Cell Biol. 27(20):7345-53.
more info or order :
American Research Products product webpage
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
www.arp1.com
(800) 832-2611
headquarters: USA