American Research Products

protein

GADD153,1-169aa, Human, His-tagged, Recombinant, E.coli

01-2002

20 ug

199.00 USD

01-2002

GADD153,1-169aa, Human, His-tagged, Recombinant, E.coli

Recombinant Protein

20 ug

199.00 USD

GADD153, also known as DNA-damage-inducible transcript 3 (DDIT3), is a basic domain-leucine zipper(bZIP) transcription factor of C/EBP family. This protein has been shown to be up-regulated by several stresses, such as amino acid or glucose starvation, endoplasmic reticulum (ER) stress, osmotic stress and hypoxia. GADD153 protein may play a role in ER stress-mediated apoptosis and in disease including diabetes, brain ischemia and neurodegenerative disease. Recombinant GADD153 fused with His-tag, was expressed in E.coli and purified by conventional chromatography techniques.

> 90% by SDS - PAGE

Liquid in 20mM Tris pH8.0, 20% Glycerol

1 mg/ml (determined by Bradford assay)

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Oyadomari S. and Mori M., et al.(2004) Cell death and differentiation,11: 381-389.Robert M. Silva.,et al:(2005) Journal of Neurochemistry ;95(4):974-986.