American Research Products

protein

Frataxin, 42-210aa, Human, His tag, E.coli, Recombinant

01-1757

10 ug

209.00 USD

01-1757

Frataxin, 42-210aa, Human, His tag, E.coli, Recombinant

Recombinant Protein

10 ug

209.00 USD

Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia. Recombinant Frataxin protein was expressed in E.coli and purified by using conventional chromatography techniques.

> 95% by SDS-PAGE

Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.

1 mg/ml (determined by Bradford assay)

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Campuzano V., et al. (1996) Science. 271(5254):1423-7.Shan Y., et al. (2007) Hum Mol Genet. 16(8):929-41.