American Research Products

protein

MAPK1, 1-360aa, Human, His tag, E.coli, Recombinant

01-1755-1

10 ug

139.00 USD

01-1755-1

MAPK1, 1-360aa, Human, His tag, E.coli, Recombinant

Recombinant Protein

10 ug

139.00 USD

MAPK1, also known as ERK(extracellular signal-regulated kinase), acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Recombinant human MAPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

> 95% by SDS - PAGE

Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.

1 mg/ml (determined by Bradford assay)

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Hu S., et al. (2009) Cell. 139(3):610-22.McGargill MA., et al. (2009) J Immunol. 183(8):4838-42.