American Research Products

protein

ACADVL, 41-655aa, Human, His tag, E.coli, Recombinant

01-1752-VL

10 ug

169.00 USD

01-1752-VL

ACADVL, 41-655aa, Human, His tag, E.coli, Recombinant

Recombinant Protein

10 ug

169.00 USD

ACADVL, also known as VLCAD, LCACD or ACAD6, is an inner mitochondrial membrane protein that belongs to the family of acyl-CoA dehydrogenases. This protein is involved in lipid metabolism and has catalytic activity toward esters of long chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA, and functions in the first step of the fatty acid beta-oxidation pathway. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Recombinant human ACADVL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

> 90 % by SDS � PAGE

Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT, 1mM EDTA, 0.1M NaCl.

0.5 mg/ml (determined by Bradford assay)

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Smelt AH., et al. (1998) Ann Neurol. 43(4):540-4.Souri M., et al. (1996) Am J Hum Genet. 58(1):97-106.