American Research Products

protein

Ketohexokinase, 1-298aa, Human, E.coli, Recombinant

01-1748

20 ug

129.00 USD

01-1748

Ketohexokinase, 1-298aa, Human, E.coli, Recombinant

Recombinant Protein

20 ug

129.00 USD

Ketohexokinase is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate, leading to consumption of ATP, formation of AMP. This protein initiates first step in the metabolism of dietary fructose and is an important regulator of hepatic glucose metabolism. It is highly found in liver, renal cortex, and small intestine. Its deficiency causes the benign hereditary metabolic disorder essential fructosuria, leading to fructose being excreted in the urine. Recombinant human Ketohexokinase was expressed in E.coli and purified by using conventional chromatography.

> 90% by SDS - PAGE

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol

1 mg/ml (determined by Bradford assay)

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Bonthron DT., et al. (2009) J Histochem Cytochem. 57(8):763-74.Schermerhorn T., et al. (2009) Res Vet Sci. 87(1):115-7.