product summary
Loading...
company name :
American Research Products
product type :
protein
product name :
Alcohol dehydrogenase, 1-325aa, Human, E.coli, Recombinant
catalog :
01-1746
quantity :
20 ug
price :
129.00 USD
product information
Catalog Number :
01-1746
Product Name :
Alcohol dehydrogenase, 1-325aa, Human, E.coli, Recombinant
Product Type :
Recombinant Protein
Size :
20 ug
List Price :
129.00 USD
Product Description :
Alcohol dehydrogenase [NADP+] (AKR1A1) is a member of the aldo/keto reductase superfamily and catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. This protein is closely related (65% identity) to aldose reductase, an enzyme involved in the pathogenesis of some diabetic and galactosemic complications. It plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Recombinant human Alcohol dehydrogenase was expressed in E.coli and purified by using conventional chromatography techniques.
Purity :
> 90% by SDS - PAGE
Packaging :
Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 50mM NaCl, 10% glycerol
Concentration :
1 mg/ml (determined by Bradford assay)
Storage :
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
General References :
Bohren KM., et al. (1989) J Biol Chem. 264(16): 9547-51.Vander Jaqt DL., et al. (1990) J Biol Chem. 265(19):10912-8.
company information
American Research Products
135 Beaver Street, Suite 204
Waltham, MA 02452
orders@arp1.com
www.arp1.com
(800) 832-2611
headquarters: USA