American Research Products

protein

Stress-induced-phosphoprotein 1, 1-543aa,Human, His tag, E.coli, Recombinant

01-1744

10 ug

149.00 USD

01-1744

Stress-induced-phosphoprotein 1, 1-543aa,Human, His tag, E.coli, Recombinant

Recombinant Protein

10 ug

149.00 USD

Stress-induced-phosphoprotein1 (STI1), also known as HOP, belongs to the large group of co-chaperones. The main function of STI1 is to link Hsp70 and Hsp90 together. But recent investigations indicate that it also modulates the chaperone activities of the linked proteins and possibly interacts with other chaperones and proteins. It forms a complex with HSC70 and HSPCA/HSP-86 and HSPCB/HSP-84, as well as interacting with PACRG. Recombinant human STI1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

> 90% by SDS - PAGE

Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

1 mg/ml (determined by Bradford assay)

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Johnson BD., et al. (1998) J Biol Chem. 273(6):3679-86.Van Der Spuy J., et al. (2001) Biochem J. 21:462-469.