product summary
company name :
Alpha Diagnostics
product type :
antibody
product name :
Rabbit Anti-Metal Transporter Protein (MTP1) Antibody, Unconjugated
catalog :
MTP11-A
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, pigs
application :
western blot, immunohistochemistry, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a, s3c
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1c
Bao W, Pang P, Zhou X, Hu F, Xiong W, Chen K, et al. Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease. Cell Death Differ. 2021;28:1548-1562 pubmed publisher
  • immunohistochemistry - frozen section; pigs ; loading ...; fig 5d
Mazgaj R, Szudzik M, Lipiński P, Jończy A, Smuda E, Kamyczek M, et al. Effect of Oral Supplementation of Healthy Pregnant Sows with Sucrosomial Ferric Pyrophosphate on Maternal Iron Status and Hepatic Iron Stores in Newborn Piglets. Animals (Basel). 2020;10: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1g
Santana Codina N, Gableske S, Quiles Del Rey M, Małachowska B, Jedrychowski M, Biancur D, et al. NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms. Haematologica. 2019;: pubmed publisher
  • western blot; mouse; fig 1h
Schwartz A, Das N, Ramakrishnan S, Jain C, Jurkovic M, Wu J, et al. Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload. J Clin Invest. 2019;129:336-348 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:150; loading ...; fig 2d
Choi Y, Lin C, Risso D, Chen S, Kim T, Tan M, et al. Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells. Science. 2017;355: pubmed publisher
  • western blot; rat; 1:2000; fig 2
Huebner S, Blohowiak S, Kling P, Smith S. Prenatal Alcohol Exposure Alters Fetal Iron Distribution and Elevates Hepatic Hepcidin in a Rat Model of Fetal Alcohol Spectrum Disorders. J Nutr. 2016;146:1180-8 pubmed publisher
  • western blot; mouse; 1:800
Zarruk J, Berard J, Passos Dos Santos R, Kroner A, Lee J, Arosio P, et al. Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation. Neurobiol Dis. 2015;81:93-107 pubmed publisher
  • western blot; rat
Dongiovanni P, Lanti C, Gatti S, Rametta R, Recalcati S, Maggioni M, et al. High fat diet subverts hepatocellular iron uptake determining dysmetabolic iron overload. PLoS ONE. 2015;10:e0116855 pubmed publisher
  • western blot; rat
Simpson I, Ponnuru P, Klinger M, Myers R, Devraj K, Coe C, et al. A novel model for brain iron uptake: introducing the concept of regulation. J Cereb Blood Flow Metab. 2015;35:48-57 pubmed publisher
  • immunohistochemistry; mouse; 1:100
  • western blot; mouse
Ikeda Y, Ozono I, Tajima S, Imao M, Horinouchi Y, Izawa Ishizawa Y, et al. Iron chelation by deferoxamine prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction. PLoS ONE. 2014;9:e89355 pubmed publisher
  • western blot; mouse; 1:500; fig 1a
Huang M, Austin C, Sari M, Rahmanto Y, Ponka P, Vyoral D, et al. Hepcidin bound to ?2-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels. J Biol Chem. 2013;288:25450-65 pubmed publisher
  • western blot; human; 1:1000; fig 1e
Straud S, Zubovych I, De Brabander J, Roth M. Inhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines. PLoS ONE. 2010;5:e11629 pubmed publisher
Yu W, An S, Shao T, Xu H, Chen H, Ning J, et al. Active compounds of herbs ameliorate impaired cognition in APP/PS1 mouse model of Alzheimer's disease. Aging (Albany NY). 2019;11:11186-11201 pubmed publisher
Gallitz I, Lofruthe N, Traeger L, Baumer N, Hoerr V, Faber C, et al. Deficiency of the BMP Type I receptor ALK3 partly protects mice from anemia of inflammation. BMC Physiol. 2018;18:3 pubmed publisher
Gajowiak A, Styś A, Starzyński R, Bednarz A, Lenartowicz M, Staroń R, et al. Mice Overexpressing Both Non-Mutated Human SOD1 and Mutated SOD1(G93A) Genes: A Competent Experimental Model for Studying Iron Metabolism in Amyotrophic Lateral Sclerosis. Front Mol Neurosci. 2015;8:82 pubmed publisher
Deschemin J, Allouche S, Brouillard F, Vaulont S. Iron Homeostasis and Inflammatory Status in Mice Deficient for the Cystic Fibrosis Transmembrane Regulator. PLoS ONE. 2015;10:e0145685 pubmed publisher
Dong X, Gao W, Kong W, Xie H, Peng Y, Shao T, et al. Neuroprotective effect of the active components of three Chinese herbs on brain iron load in a mouse model of Alzheimer's disease. Exp Ther Med. 2015;9:1319-1327 pubmed
Lesjak M, Hoque R, Balesaria S, Skinner V, Debnam E, Srai S, et al. Quercetin inhibits intestinal iron absorption and ferroportin transporter expression in vivo and in vitro. PLoS ONE. 2014;9:e102900 pubmed publisher
Fuqua B, Lu Y, Darshan D, Frazer D, Wilkins S, Wolkow N, et al. The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice. PLoS ONE. 2014;9:e98792 pubmed publisher
Dostalikova Cimburova M, Balusikova K, Kratka K, Chmelikova J, Hejda V, Hnaníček J, et al. Role of duodenal iron transporters and hepcidin in patients with alcoholic liver disease. J Cell Mol Med. 2014;18:1840-50 pubmed publisher
Dostalikova Cimburova M, Kratka K, Balusikova K, Chmelikova J, Hejda V, Hnaníček J, et al. Duodenal expression of iron transport molecules in patients with hereditary hemochromatosis or iron deficiency. J Cell Mol Med. 2012;16:1816-26 pubmed publisher
company information
Alpha Diagnostics
6203 Woodlake Center San Antonio, Texas 78244
http://www.4adi.com
headquarters: USA