chemical

ZD 9379

Z-120

Z-120_10 mg

ZD 9379

Non Antibodies

S. Molecules

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

ZD 9379 is a neuroprotective, soluble and potent antagonist of the N-methyl-D-aspartate (NMDA) receptor. The compound acts at the glycine site on the NMDA receptor. This site is used as a therapeutic target for acute focal ischemia. ZD 9379 has the ability to pass the blood brain barrier and reduce infract size and frequency in models of ischemic stroke1,2.The NMDA receptors are a ligand-gated ion channel which is widely distributed in the central nervous system (CNS) and plays an important role in a variety of cellular processes and brain functions such as, synaptic plasticity, addiction and stroke. NMDA receptors mediate physiological functions such as learning and memory formation. They also play a role in glutamate excitotoxicity and are involved in many neurodegenerative conditions including Alzheimer's disease3.

Alomone Labs

NMDA receptors

ZD 9379 (#Z-120) is a highly pure, synthetic, and biologically active compound.

An Antagonist of NMDA Receptors

383.79

Synthetic

C19H14ClN3O4.

50 nM - 1 µM.

ZD 9379 is a NMDA receptor antagonist1.

20 mM in DMSO. Centrifuge all product preparations before use (10000 x g for 1 min).

20 mM in DMSO. Centrifuge all product preparations before use (10000 x g for 1 min).

Up to four weeks at 4°C or three months at -20°C.

1-2 Business Days

Israel/IL

Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.

>99%

170142-20-8

Lyophilized powder.

Contact Alomone Labs for technical support and product customization

41116134

Yes

7-chloro-2-(4-methoxy-2-methylphenyl)-3,5-dihydropyridazino[4,5-b]quinoline-1,4,10-trione.