chemical

TTA-P2 (S-enantiomer)

T-210

T-210_1 mg

TTA-P2 (S-enantiomer)

Non Antibodies

S. Molecules

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

TTA-P2 is a novel, potent and selective T-type CaV channel blocker. In thalamocortical and reticular neurons, it blocks T-type currents with an IC50 of 22 nM without affecting high voltage Ca2+ channels1. In rat DRGs, it blocks T-type currents with an IC50 of 100 nM and stabilizes the channel in the inactive state2.TTA-P2 has the potential of acting as an antinociceptive agent2.

Alomone Labs

CaV3 channels

TTA-P2 (S-enantiomer) (#T-210) is a highly pure, synthetic, and biologically active compound.

A Blocker of T-Type CaV Channels

431

Synthetic

C21H29Cl2FN2O2.

0.05-10 µM.

TTA-P2 blocks T-type currents in DRGs with IC50 of 100 nM and 22 nM in thalamocortical and reticular neurons1,2.

50 mM in DMSO. Centrifuge all product preparations before use (10,000 x g for 1 min).

50 mM in DMSO. Centrifuge all product preparations before use (10,000 x g for 1 min).

Up to four weeks at 4°C or three months at -20°C.

1-2 Business Days

Israel/IL

Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.

>99%

1072018-68-8

Lyophilized powder.

Contact Alomone Labs for technical support and product customization

41116134

Yes

Electrophysiology

(S)-3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide.