Taurine | Alomone Labs T-130 product information

product summary

company name :

Alomone Labs

product type :

chemical

product name :

Taurine

catalog :

T-130

more info or order :

Alomone Labs product webpage

citations: 1

Reference
Cui X, Navneet S, Wang J, Roon P, Chen W, Xian M, et al. Analysis of MTHFR, CBS, Glutathione, Taurine, and Hydrogen Sulfide Levels in Retinas of Hyperhomocysteinemic Mice. Invest Ophthalmol Vis Sci. 2017;58:1954-1963 pubmed publisher

image

image 1 :

Expression of GluA2 in rat PC12 cells - Cell surface detection ofGluA2 in live intact rat pheochromocytoma PC12 cells. A. Extracellular staining of cells using Guinea pig Anti-GluR2 (GluA2) (extracellular) Antibody(#AGP-073) (1:50) followed by goat anti-guinea pig-AlexaFluor-594 secondary antibody (red). B. Live image of the cells. C. Merge of A and B.

product information

CAT :

T-130

SKU :

T-130_10 g

Product Name :

Taurine

Group Type :

Non Antibodies

Product Type :

S. Molecules

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

Product Page - Scientific background :

Taurine (2-aminoethanesulfonic acid) is a β-amino acid, one of the most abundant free amino acids found in vertebrates. Taurine can be present in many tissues including brain, myocardium, and kidney. It plays an important role in several physiological processes including cardiac contraction, antioxidation, blunting of hypertension, bile acid conjugation, maintenance of calcium homeostasis, osmoregulation, and membrane stabilization.Taurine acts as an endogenous partial agonist at the inhibitory glycine receptor (GlyR)1,2.The glycine receptor is a member of the ligand-gated ion channel (LGIC) superfamily. The receptor mediates fast inhibitory neurotransmission in the mammalian spinal cord and parts of the brain3.

Supplier :

Alomone Labs

Target :

Glycine receptor, Taurine transporter

Long Description :

Taurine (#T-130) is a highly pure, synthetic, and biologically active compound.

Short Description :

An Endogenous Partial Agonist of Glycine Receptors and Taurine Transporters

MW :

125.15

Synonyms :

2-Aminoethylsulfonic acid, Tauphon

Source :

Synthetic

Molecular formula :

C2H7NO3S.

Effective Concentration :

0.05-5 mM.

Activity :

Taurine is a Glycine receptor (GlyR) partial agonist (EC50=1.7 mM)1. It displaces [3H]Strychnine bound to GlyR α1 expressing 293 cells membrane fraction (Ki=170 µM)2.

Reconstitution and Solubility :

>100mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).

Solubility :

>100mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).

Storage of solutions :

Up to four weeks at 4°C or three months at -20°C.

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.

Purity :

>99%

CAS No :

107-35-7

Form :

Lyophilized Powder

Comment :

Contact Alomone Labs for technical support and product customization

UNSPSC :

41116134

Bioassay Tested :

Yes

Chemical Name :

2-aminoethanesulfonic acid.

more info or order :

Alomone Labs product webpage