chemical

PD-161989 2-hydroxyethanesulfonate

P-285

P-285_10 mg

PD-161989 2-hydroxyethanesulfonate

Non Antibodies

S. Molecules

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

Glutamate is the major excitatory neurotransmitter in the central nervous system (CNS). AMPA receptors are ionotropic glutamate channels, play a key role in the development and function of the nervous system and are essential in memory and learning1.PD-161989 2-hydroxyethanesulfonate is a synthetic, potent and selective antagonist of AMPA glutamate receptors. It has an effective concentration of 0.1-100 µM.

Alomone Labs

AMPA receptors

PD-161989 2-hydroxyethanesulfonate (#P-285) is a highly pure, synthetic, and biologically active compound.

An Antagonist of AMPA Receptors

430.43

PD-161989 2-hydroxyethanesulfonic acid salt , PD-161989 isethionate salt

Synthetic

C16H22N4O8S.

0.1-100 µM.

PD-161989 2-hydroxyethanesulfonate is an AMPA receptor antagonist.

Centrifuge the vial before adding solvent (10,000 x g for 5 minutes) to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Tap the vial to aid in dissolving the lyophilized product. Tilt and gently roll the liquid over the walls of the vial. Avoid vigorous vortexing. Light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 µM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20°C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity

Up to 20 mM in H2O or DMSO (slowly, clear yellow solution). Centrifuge all products before reconstitution (10000 x g 5 min).

Up to four weeks at 4°C or three months at -20°C. It is recommended to aliquot reconstituted stock solutions.

1-2 Business Days

Israel/IL

Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.

>99%

1262770-05-7

Lyophilized powder.

Contact Alomone Labs for technical support and product customization

41116134

Yes

2-hydroxyethanesulfonic acid;6-methyl-7-nitro-5-(pyrrolidin-1-ylmethyl)-1,4-dihydroquinoxaline-2,3-dione.