Nimodipine | Alomone Labs N-150 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Alomone Labs

product type :

chemical

product name :

Nimodipine

catalog :

N-150

quantity :

250 mg, 1 g, 5 g, 10 g

citations: 2

Reference
Sieber A, Min R, Nevian T. Non-Hebbian long-term potentiation of inhibitory synapses in the thalamus. J Neurosci. 2013;33:15675-85 pubmed publisher
Lv P, Sihn C, Wang W, Shen H, Kim H, Rocha Sanchez S, et al. Posthearing Ca(2+) currents and their roles in shaping the different modes of firing of spiral ganglion neurons. J Neurosci. 2012;32:16314-30 pubmed publisher

product information

Vendor :

Alomone Labs Ltd.

Item Name :

Nimodipine

Catalog Number :

N-150

Size :

250 mg, 1 g, 5 g, 10 g

Type :

Antagonists Inhibitors

Molecule Name :

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5 pyridinedicarboxylic acid 2-methyloxyethyl 1-methylethyl ester.

CAS Number :

66085-59-4

Source/Expression System :

Synthetic

Activity :

Nimodipine is a dihydropyridine that acts as L-type, voltage-gated Ca2+ channel blocker and is used in the clinic to treat hypertension. Nimodipine inhibits L- type Cav channels with IC50 of about 10 #956M and has little effect on other Cav channels at this concentration.

Molecular Weight :

418.4

Gene symbol :

CACNA1S, CACNA1C, CACNA1D, CACNA1F

Target :

L-type Ca2+ channels

Formula :

C21H26N2O7

Format :

Lyophilized/solid.

Purity :

99%

Product Description :

A Potent Blocker of L-Type Cav Channels

Category :

Ca2+ signaling, Ca2+ signalling, Ion Channels, Chemicals and Reagents, Inhibitors, Biomolecules, Blockers, Antagonists

Research Area :

Cardiovascular, Cardiac, Heart, Alzheimer's Disease, Neurodegenerative Disorders, Neuroscience