This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Alomone Labs
product type :
chemical
product name :
Lidocaine hydrochloride
catalog :
L-145
quantity :
25 g, 50 g
product information
Vendor :
Alomone Labs Ltd.
Item Name :
Lidocaine hydrochloride
Catalog Number :
L-145
Size :
25 g, 50 g
Type :
Antagonists Inhibitors
Molecule Name :
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride.
CAS Number :
73-78-9
Source/Expression System :
Synthetic
Activity :
Lidocaine blocks both TTX-sensitive and TTX-resistant Nav channels in DRG neurons with IC50 of 42 and 210 muM, respectively. Lidocaine was more effective in blocking the inactivated state (IC50 60 muM for TTX-resistant in the inactivated state).
Molecular Weight :
270.8
Gene symbol :
SCN1A, SCN2A, SCN3A, SCN5A, SCN9A, SCN8A, SCN10A, SCN11A, SCN4A, HCN1, HCN2, HCN3, HCN4
Target :
Nav, HCN channels
Formula :
C14H23N2OCl
Format :
Lyophilized/solid.
Purity :
0.98
Product Description :
A State-Dependent Blocker of Neuronal Nav Channels
Category :
Ion Channels, Chemicals and Reagents, Inhibitors, Biomolecules, Blockers, Antagonists
Research Area :
Inflammation, Neuroinflammation, Pain, Nociception, Epilepsy, Neuroscience
company information
Alomone Labs
Jerusalem BioPark (JBP), Hadassah Ein Kerem
P.O. Box 4287
Jerusalem 9104201
info@alomone.com
http://www.alomone.com
972 2 531 8002
headquarters: Israel