This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Alomone Labs
product type :
chemical
product name :
Lidocaine
catalog :
L-105
quantity :
10 g, 25 g, 50 g
product information
Vendor :
Alomone Labs Ltd.
Item Name :
Lidocaine
Catalog Number :
L-105
Size :
10 g, 25 g, 50 g
Type :
Antagonists Inhibitors
Molecule Name :
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide.
CAS Number :
137-58-6
Source/Expression System :
Synthetic
Activity :
Lidocaine is a commonly used local anesthetic as well as an antiarrythmic drug, which is a potent and selective blocker of voltage gated sodium channels (Nav). Lidocaine is a state dependent inhibitor of the channel, with stronger inhibitory action towards the inactivated state. Once compared directly for its inhibitory effects on TTX-resistant currents and on the TTX-sensitive Nav1.2 channel, it was demonstrated that both types of currents are sensitive to Lidocaine in an activity dependent manner.
Molecular Weight :
234.3
Gene symbol :
SCN1A, SCN2A, SCN3A, SCN5A, SCN9A, SCN8A, SCN10A, SCN11A, SCN4A, HCN1, HCN2, HCN3, HCN4
Target :
Nav, HCN channels
Formula :
C14H22N2O
Format :
Lyophilized/solid.
Purity :
99%
Product Description :
A State-Dependent Nav Channel Inhibitor
Category :
Ion Channels, Chemicals and Reagents, Inhibitors, Biomolecules, Blockers, Antagonists
Research Area :
Inflammation, Neuroinflammation, Pain, Nociception, Epilepsy, Neuroscience
company information

Alomone Labs
Jerusalem BioPark (JBP), Hadassah Ein Kerem
P.O. Box 4287
Jerusalem 9104201
P.O. Box 4287
Jerusalem 9104201
info@alomone.com
http://www.alomone.com972 2 531 8002
headquarters: Israel
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