Cytochalasin E | Alomone Labs C-550 product information

product summary

company name :

Alomone Labs

product type :

chemical

product name :

Cytochalasin E

catalog :

C-550

more info or order :

Alomone Labs product webpage

image

image 1 :

Expression of Corticotropin-releasing factor receptor 1 in mouse brain - Immunohistochemical staining of mouse hippocampus and mouse cerebellum usingAnti-CRF1/CRHR1 (extracellular) Antibody(#ACR-050) (1:600). A. CRF1 staining (green) in the cerebellum appears in cerebellar molecular layer (MOL). B. CRF1staining (green)in the hippocampus appears in soma (horizontal arrows) and dendrites of pyramidal neurons (arrow). In both panels DAPI was used as the counterstain.

image 2 :

Alomone Labs Cytochalasin E inhibits actin polymerization in C6 glioma cells. - Cells were incubated in the absence (A) or presence (B) of 10 MCytochalasinE (#C-550) for 1 h at 37C. The figure shows dual staining using Rhodamine-conjugated-Palloidine for actin filament staining (red) and DAPI for nucleus staining (blue).

product information

CAT :

C-550

SKU :

C-550_1 mg

Product Name :

Cytochalasin E

Group Type :

Non Antibodies

Product Type :

S. Molecules

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.

Storage before Reconstitution :

The product is shipped as a lyophilized powder at room temperature. Upon receipt, store the product at -20°C. Protect from moisture.

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

Product Page - Scientific background :

Cytochalasins are a group of fungal toxin metabolites which bind to actin and alter its polymerization. Cytochalasins bind to the barbed end of the actin filament and prevent both the association and dissociation of actin subunits by inhibiting cell microtubule formation, cell division and cell migration.1-4Cytochalasin E induced a rapid and sustained elevation of intracellular free Ca2+ in B lymphocytes by increasing the extracellular Ca2+ influx.5,6

Supplier :

Alomone Labs

Long Description :

Cytochalasin E (#C-550) is a highly pure, natural, and biologically active compound.

Short Description :

An Anticancer Compound and a Protein Synthesis and Transport Inhibitor

MW :

495.6

Source :

Natural

Molecular formula :

C28H33NO7.

Effective Concentration :

0.1-10 µM.

Activity :

Cytochalasin E is a fungal toxin which inhibits actin polymerization and blocks the formation of microtubules by inhibiting cell division and cell migration1-4.

Reconstitution and Solubility :

Water, DMSO, ethanol, methanol, acetone. Centrifuge all product preparations before use (10000 x g 5 min).

Solubility :

Water, DMSO, ethanol, methanol, acetone. Centrifuge all product preparations before use (10000 x g 5 min).

Storage of solutions :

Up to two weeks at 4°C or six months at -20°C.Protect from light.

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.

Purity :

>99%

CAS No :

36011-19-5

Form :

Lyophilized powder.

Comment :

Contact Alomone Labs for technical support and product customization

UNSPSC :

41116134

Bioassay Tested :

Yes

Chemical Name :

21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22- trione,6,7-epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-,(7S,13E,16S,18R,19E)-.

more info or order :

Alomone Labs product webpage