Anti-Somatostatin Receptor Type 2 Antibody | Alomone Labs ASR-002 product information

product summary

company name :

Alomone Labs

product type :

antibody

product name :

Anti-Somatostatin Receptor Type 2 Antibody

catalog :

ASR-002

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

Alomone Labs product webpage

citations: 1

Reference
Foiani G, Guelfi G, Chiaradia E, Mancini F, Trivelli C, Vitellozzi G, et al. Somatostatin Receptor 2 Expression in Canine Meningioma. J Comp Pathol. 2019;166:59-68 pubmed publisher

image

image 1 :

Western blot analysis of rat brain membranes: - 1. Anti-Somatostatin Receptor Type 2 Antibody (#ASR-002), (1:400).2. Anti-Somatostatin Receptor Type 2 Antibody, preincubated with Somatostatin Receptor Type 2 Blocking Peptide (#BLP-SR002).

image 2 :

Western blot analysis of rat brain membranes: - 1.Anti-Somatostatin Receptor Type 2Antibody (#ASR-002) (1:400).2. Anti-Somatostatin Receptor Type 2 Antibody preincubated with the negative control antigen.

image 3 :

Peptide (C)DYVGKLAGRLRD corresponding to amino acid residues 23-34 of mouse S1PR3 (AccessionQ9Z0U9). Extracellular N-terminus.

product information

CAT :

ASR-002

SKU :

ASR-002-CF_0.2 ml

Product Name :

Anti-Somatostatin Receptor Type 2 Antibody

Group Type :

Antibodies

Product Type :

Antibodies

Clonality :

Polyclonal

Accession :

P30680

Applications :

IHC WB

Reactivity :

Human Rat Mouse

Host :

Rabbit

Blocking Peptide :

BLP-SR002

Homology :

Mouse, human - identical

Formulation :

PBS pH7.4

isotype :

Rabbit IgG

Peptide confirmation :

Confirmed by amino acid analysis and mass spectrometry

Reconstitution :

0.2 ml double distilled water (DDW).

Antibody Concentration After Reconstitut ... :

1 mg/ml

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Preservative :

No Preservative

Immunogen Location :

Intracellular, C-terminus

Label :

Unconjugated

Storage Before Reconstitution :

The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

immunogen source species :

Rat

Sequence :

(C)ERSDSKQDKSRLNETTETQRT corresponding to residues 339-359 of rat SSTR2

Product Page - Scientific background :

Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues1. In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain, it acts as a neurotransmitter in both a stimulatory and an inhibitory manner1,2.Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4, and SSTR5), which are encoded by five genes1,2. Expression of the different receptors is developmentally regulated in a time- and tissue-specific manner2.Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids, and breast tumors3. Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in vivo imaging of tumors that are positive for somatostatin receptors4.In general, SSTR2 is the most common SSTR subtype found in human tumors, followed by SSTR1, with SSTR3 and SSTR4 being less common.

Applications may also work in :

IHC WB

Supplier :

Alomone Labs

Target :

SSTR2a, SS2R, Smstr2, SRIF1A

Short Description :

A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 2

Long Description :

Anti-Somatostatin Receptor Type 2 Antibody (#ASR-002) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize SSTR2 from human, mouse, and rat samples.

Negative Control :

BLP-SR002

Positive Control :

Synonyms :

SSTR2a, SS2R, Smstr2, SRIF1A

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot

Specifictiy :

SSTR2

Form :

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.

Comment :

Contact Alomone Labs for technical support and product customization

Species reactivity key :

H- Human, M- Mouse, R- Rat

Is Toxin :

Purity :

Affinity purified on immobilized antigen.

UNSPSC :

41116161

Clone :

Standard quality control of each lot :

Western blot analysis

Antigen preadsorption control :

1 µg peptide per 1 µg antibody

Application Dilutions: Immunohistochemis ... :

Contact Alomone for information

Application Dilutions: Western blot wb :

1:400

more info or order :

Alomone Labs product webpage