Anti-Somatostatin Receptor Type 1 (extracellular) Antibody | Alomone Labs ASR-001 product information

product summary

company name :

Alomone Labs

product type :

antibody

product name :

Anti-Somatostatin Receptor Type 1 (extracellular) Antibody

catalog :

ASR-001

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

reactivity :

mouse, rat

application :

western blot, immunohistochemistry

more info or order :

Alomone Labs product webpage

citations: 1

Reference
Lukomska A, Dobrzanski G, Liguz Lecznar M, Kossut M. Somatostatin receptors (SSTR1-5) on inhibitory interneurons in the barrel cortex. Brain Struct Funct. 2020;225:387-401 pubmed publisher

image

image 1 :

Western blot analysis of rat brain lysate: - 1. Anti-Somatostatin Receptor Type 1 (extracellular) Antibody (#ASR-001), (1:200).2. Anti-Somatostatin Receptor Type 1 (extracellular) Antibody, preincubated with Somatostatin Receptor Type 1 (extracellular) Blocking Peptide (#BLP-SR001).

image 2 :

Western blot analysisof rat brain lysate: - 1.Anti-Somatostatin Receptor Type 1(extracellular)Antibody (#ASR-001)(1:200).2. Anti-Somatostatin Receptor Type 1(extracellular) Antibody preincubated with the control peptide antigen.

image 3 :

Alomone Labs ANA-12 inhibits BDNF-induced ERK1/2 (p42/44 MAPK) phosphorylation in TrkB-expressing HEK 293 cells. - Serum-deprived cells were stimulated with 1 ng/ml Recombinant human BDNF protein (#B-250) in the presence of 0 M 100 M and 200 MANA-12(#A-215). Cell proteins were resolved by SDS-PAGE and probed with anti-phospho-ERK1/2.

product information

CAT :

ASR-001

SKU :

ASR-001-CF_0.2 ml

Product Name :

Anti-Somatostatin Receptor Type 1 (extracellular) Antibody

Group Type :

Antibodies

Product Type :

Antibodies

Clonality :

Polyclonal

Accession :

P28646

Applications :

IHC WB

Reactivity :

Rat Mouse

Host :

Rabbit

Blocking Peptide :

BLP-SR001

Homology :

Mouse - identical; human - 13/15 amino acid residues identical

Formulation :

PBS pH7.4

isotype :

Rabbit IgG

Peptide confirmation :

Confirmed by amino acid analysis and mass spectrometry

Reconstitution :

0.2 ml double distilled water (DDW).

Antibody Concentration After Reconstitut ... :

1 mg/ml

Storage After Reconstitution :

The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Preservative :

No Preservative

Immunogen Location :

Extracellular, N-terminus

Label :

Unconjugated

Storage Before Reconstitution :

The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Shipping and storage :

Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C

immunogen source species :

Rat

Sequence :

CSRGPGSGAADGMEE, corresponding to amino acid residues 26-40 of rat SSTR1

Product Page - Scientific background :

Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both a stimulatory and inhibitory manner.1,2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.2Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.4

Applications may also work in :

IHC WB

Supplier :

Alomone Labs

Target :

SSTR1, SS1R, SRIF-2, SRIF2A

Short Description :

A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 1

Long Description :

Anti-Somatostatin Receptor Type 1 (extracellular) Antibody (#ASR-001) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize SSTR1 from rat, mouse, and human samples.

Negative Control :

BLP-SR001

Positive Control :

Synonyms :

SSTR1, SS1R, SRIF-2, SRIF2A

Lead Time :

1-2 Business Days

Country of origin :

Israel/IL

Applications key :

CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot

Specifictiy :

SSTR1

Form :

Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.

Comment :

Contact Alomone Labs for technical support and product customization

Species reactivity key :

H- Human, M- Mouse, R- Rat

Is Toxin :

Purity :

Affinity purified on immobilized antigen.

UNSPSC :

41116161

Clone :

Standard quality control of each lot :

Western blot analysis

Antigen preadsorption control :

1 µg peptide per 1 µg antibody

Application Dilutions: Immunohistochemis ... :

1:1000

Application Dilutions: Western blot wb :

1:200

more info or order :

Alomone Labs product webpage